Santa Croce Vacations from $1,538

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel de l'Alboro

Hotel de l'Alboro

3 out of 5
Venice City Center
Save 100% on your flight
Price was $2,163, price is now $1,538 per person
$1,538
per person
Sep 9 - Sep 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (47 reviews)
Clean place. Just AC did not run unless you were in there

Reviewed on Jun 19, 2026

Cà Bonfadini Historic Experience

Cà Bonfadini Historic Experience

5 out of 5
Cannaregio
Save 100% on your flight
Price was $3,424, price is now $2,108 per person
$2,108
per person
Sep 9 - Sep 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (229 reviews)
Lovely location away from the crowds but not so far from Rialto etc. Good quality hotel. Very clean!! Cleaner than many other 5 star hotels I've experienced. Some great food places nearby by the canalside too. Especially the restaurant Very Good. With another travel companion, I would have liked to have tried the hotel restaurant. Would certainly stay here again if staying in Carneggio.

Reviewed on Jun 3, 2026

Ca' Sagredo

Ca' Sagredo

5 out of 5
Cannaregio
Save 100% on your flight
Price was $2,620, price is now $1,744 per person
$1,744
per person
Aug 6 - Aug 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.2/10 Wonderful! (499 reviews)
This hotel was wonderful, but the staff are the best staff out of any hotel. Some of the nicest people ever—especially Ricardo. He was the best, and went truly above and beyond. Once in a lifetime service and accommodations. Also great location. Take advantage of the boat service + deck service, and if there is any question the staff will help. The only issue was the room cleanliness. There were random bits of food on the floor, and the cleaning staff left their gloves on the floor (I have a photo). Would recommend again.

Reviewed on May 27, 2026

Hotel Palazzetto Madonna

Hotel Palazzetto Madonna

4 out of 5
San Polo
Save 100% on your flight
Price was $2,487, price is now $1,682 per person
$1,682
per person
Sep 9 - Sep 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.2/10 Wonderful! (1,003 reviews)
This hotel is right on the canal. It is very convenient to St Marks Square as well as the pick up location for our car to the cruise port. Great breakfast.

Reviewed on Jun 19, 2026

Colombina Hotel

Colombina Hotel

4 out of 5
Castello
Save 100% on your flight
Price was $2,779, price is now $1,910 per person
$1,910
per person
Sep 9 - Sep 14
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.4/10 Exceptional! (1,005 reviews)
Great location, rooms are a great Venice vib. Book it and enjoy italy

Reviewed on Jun 6, 2026

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Venice City Center

Venice City Center

5 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

Find hotels in Venice City Center

Santa Croce Hotel Deals

Santa Chiara Hotel

Santa Chiara Hotel

4.5 out of 5
Santa Croce 548 Venice VE
Fully refundableReserve now, pay when you stay
$274 nightly
The price is $312 total per night from Jul 16 to Jul 17
$312 total
Jul 16 - Jul 17
Total with taxes and fees
9.4/10 Exceptional! (362 reviews)
"Staff was wonderful and attentive.. stayed here to take advantage of both “land” travel (to the lakes and Verona) and local transit - plz Roma stop right outside the door! Perfecto!"

Reviewed on Jun 15, 2026

Santa Chiara Hotel
Hotel Canal Grande

Hotel Canal Grande

4 out of 5
Santa Croce 932 Venice VE
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $259 total per night from Jul 20 to Jul 21
$259 total
Jul 20 - Jul 21
Total with taxes and fees
9.6/10 Exceptional! (1,002 reviews)
"staff is very helpful and nice"

Reviewed on Jun 19, 2026

Hotel Canal Grande
Hotel Arlecchino

Hotel Arlecchino

3 out of 5
Fondamenta Delle Burchielle Venice VE
$197 nightly
The price is $225 total per night from Jul 21 to Jul 22
$225 total
Jul 21 - Jul 22
Total with taxes and fees
9.4/10 Exceptional! (1,003 reviews)
"This hotel was incredible. The staff was friendly, welcoming, and helpful. The hotel is perfectly located by the Piazza Roma which is the hub for the shuttle bus to the airport and the water taxis. There is also a really great restaurant right out the door to the hotel. We will definitely stay here ..."

Reviewed on Jun 19, 2026

Hotel Arlecchino
See all 6,295 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Vacations
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Discover the most popular places to visit in Santa Croce

moderne Fußgängerbrücke über den Canal Grande Venedig

Piazzale Roma

4.5/5(634 reviews)

You can learn about the local history of Venice during your trip to a top site like Piazzale Roma. Stroll along the marina or visit the churches in the area.

Piazzale Roma
Milan, Italy February 17th 2019 Fondazione Prada with reflective pool, photographed from Adriano Olivetti's square

Fondazione Prada

You can browse the exhibits at Fondazione Prada, a museum with a storied past, during your trip to Venice. Visit the area's churches or amble around its marina.

Fondazione Prada
San Simeone Piccolo

San Simeone Piccolo

San Simeone Piccolo is just one of the places to see in Venice, so why not enjoy the other things to explore during your travels? Visit the area's stunning cathedral or amble around its marina.

San Simeone Piccolo

Things to do

Venice in a Day with St. Mark's Basilica, Doge's Palace, & Gondola Ride

Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour

$182
per adult
94% of travellers recommend
Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour
Single gondola paddles down waterway in Venice

Classic 30 minutes Gondola Ride

$45
per traveler
72% of travellers recommend
Classic 30 minutes Gondola Ride
Taste of Venice: Local Tapas Tastings & Wine Tour

Venice Small Group Tour: Venetian Tapas, Wine, Spritz & Gondola Ride

$81
per adult
96% of travellers recommend
Venice Small Group Tour: Venetian Tapas, Wine, Spritz & Gondola Ride
See all activities in Venice
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.